Adverse reactions to drugs are a major public healthcare issue. Currently,
the Food and Drug Administration (FDA) publishes quarterly reports that
typically contain in the order of 200,000 adverse incidents. In such a large
number of incidents, low frequency events that may be highly clinically
significant but are often undetected. In this poster, we introduce a pixel
cell-based visualization technique with novel relevance ordering algorithm,
significance statistics computation, and semantic zooming in an x-y plan. We
are able to identify important adverse events, such as the known association
of the drug Avandia with myocardial infarction; as well as low frequency
events such as the association of Actos with bladder cancer.